Personalized medicine for individuals with Down syndrome.

Personalized medicine for individuals with Down syndrome.

Mol Genet Metab. 2011 Jul 19;

Authors: McCabe LL, McCabe ER

As the cost of whole genome analysis decreases, we have the opportunity to explore the interactions of various gene changes in an individual that lead to their particular phenotype. This will provide the ability to move from the epidemiologic study of groups, in which, the individuals are treated collectively and homogenously, to personalized medicine, and a model in which the individual is recognized and treated as a distinct entity. We will be applying personalized medicine to individuals with Down syndrome in order to understand and develop biomarkers for increased risk of co-morbidities. Personalized medicine will change the "culture of intractability" of Down syndrome.

PMID: 21807541 [PubMed - as supplied by publisher]

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Personal Genome

Personalized medicine for individuals with Down syndrome.

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Personalized medicine from Sciencedaily