Personal Genome

Archive for the ‘Ancestry and genealogy’ category

Ancestry at 23andMe: Old Roots and New Horizons

October 29, 2010

Sheridan* can hardly believe that in just a couple of weeks, she’s learned something about her deep ancestry on her mother’s side, placed herself genetically among the different populations of the world, connected with a potential fifth cousin, discovered a potential second cousin, and traced a fourth cousin shared DNA connection with her life-long friend [...]

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Ancestry at 23andMe: Finding Connections

October 22, 2010

In our last post, Sheridan* responded to her potential fifth cousin Akina and discovered that she has a potential second cousin through 23andMe’s Relative Finder feature. All of this is exciting, but she’s definitely starting to feel her lack of genealogy experience catching up with her. When she logs into her account next, though, she [...]

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Personalized medicine from Sciencedaily
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  Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific “targeted” drugs already in use for treating other cancers, scientists report. The genetic alterations – pieces of two genes fused together - showed up in a massive search of the DNA in s […]
- Scientists use old theory to discover new targets in fight against breast cancer
  Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people. Their findings provide new ways to predict and personalize the diagnosis and treatment […]
- Ovarian cancer risk related to inherited inflammation genes
  Genes that are known to be involved in inflammation were found to be related to risk of ovarian cancer. […]
- Stem cells could drive hepatitis research forward
  Researchers have produced liver-like cells from induced pluripotent stem cells. By creating liver-like cells, scientists can study why people respond differently to Hepatitis C. […]
- Genes linked to cancer could be easier to detect with liquid lasers
  Using a liquid laser, researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases. […]
- Genetic breakthrough for brain cancer in children
  Scientists have made a major genetic breakthrough that could change the way pediatric cancers are treated in the future. The researchers identified two genetic mutations responsible for up to 40 per cent of glioblastomas in children. The mutations were found to be involved in DNA regulation, which could explain the resistance to traditional treatments, and m […]
- Women with certain type of ovarian cancer and BRCA gene mutation have improved survival at 5 years
  Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved five-year overall survival, with BRCA2 carriers having the best prognosis, according to a new study. […]
- Precancer markers identified in airway epithelium cells of healthy smokers
  Smokers are more likely to have molecular features of cancerization in the large airway epithelium. Smokers with COPD had significant changes in the small airway epithelium, new research has shown. New findings could lead to development of a diagnostic test. […]
- Ganetespib showed activity in KRAS-mutant NSCLC as monotherapy and in combinations
  Novel Hsp90 inhibitor shows activity in slowing KRAS-mutant NSCLC tumor cell growth. Use with traditional chemotherapy resulted in increased cancer cell death. Phase 2b/3 trial combined with docetaxel underway. […]
- Why personalized medicine holds promise for preventing and treating diabetes
  To address the prospects for personalized medicine in diabetes, investigators have surveyed the field for existing research. […]

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